Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors. (Record no. 30131668)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02283 a2200661 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518061806.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202006s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1476-5594 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/s41388-019-1012-2 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | O'Connor, Caitlin M |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20200619 |
| 245 00 - TITLE STATEMENT | |
| Title | Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Oncogene |
| Date of publication, distribution, etc. | 01 2020 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 703-717 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amino Acid Substitution |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Arginine |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Calmodulin-Binding Proteins |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Carcinogenesis |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Resistance, Neoplasm |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MAP Kinase Signaling System |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Membrane Proteins |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mitogen-Activated Protein Kinase Kinases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Dynamics Simulation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutagenesis, Site-Directed |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neoplasms |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nerve Tissue Proteins |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Kinase Inhibitors |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Phosphatase 2 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Recombinant Proteins |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Transfection |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Tyrosine |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Xenograft Model Antitumor Assays |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leonard, Daniel |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wiredja, Danica |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Avelar, Rita A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wang, Zhizhi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schlatzer, Daniela |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bryson, Benjamin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tokala, Eesha |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Taylor, Sarah E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Upadhyay, Aditya |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sangodkar, Jaya |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gingras, Anne-Claude |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Westermarck, Jukka |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Xu, Wenqing |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | DiFeo, Analisa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brautigan, David L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Haider, Shozeb |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jackson, Mark |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Narla, Goutham |
| 773 0# - HOST ITEM ENTRY | |
| Title | Oncogene |
| Related parts | vol. 39 |
| -- | no. 3 |
| -- | p. 703-717 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/s41388-019-1012-2">https://doi.org/10.1038/s41388-019-1012-2</a> |
| Public note | Available from publisher's website |
No items available.