Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations. (Record no. 29760753)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01738 a2200493 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518042837.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201906s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 2041-1723 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/s41467-019-10363-1 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Birkinshaw, Richard W |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20190624 |
| 245 00 - TITLE STATEMENT | |
| Title | Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Nature communications |
| Date of publication, distribution, etc. | 06 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 2385 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Agents |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bridged Bicyclo Compounds, Heterocyclic |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Crystallization |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Crystallography, X-Ray |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Resistance, Neoplasm |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukemia, Lymphocytic, Chronic, B-Cell |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Binding |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proto-Oncogene Proteins c-bcl-2 |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sulfonamides |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Surface Plasmon Resonance |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gong, Jia-Nan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Luo, Cindy S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lio, Daisy |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | White, Christine A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Anderson, Mary Ann |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Blombery, Piers |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lessene, Guillaume |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Majewski, Ian J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thijssen, Rachel |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Roberts, Andrew W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huang, David C S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Colman, Peter M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Czabotar, Peter E |
| 773 0# - HOST ITEM ENTRY | |
| Title | Nature communications |
| Related parts | vol. 10 |
| -- | no. 1 |
| -- | p. 2385 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/s41467-019-10363-1">https://doi.org/10.1038/s41467-019-10363-1</a> |
| Public note | Available from publisher's website |
No items available.