The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. (Record no. 29545553)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02148 a2200649 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518032430.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202002s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1476-5551 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/s41375-019-0461-5 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Christian, Sven |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20200203 |
| 245 00 - TITLE STATEMENT | |
| Title | The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Leukemia |
| Date of publication, distribution, etc. | 10 2019 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 2403-2415 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Agents |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Apoptosis |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Differentiation |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dihydroorotate Dehydrogenase |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Enzyme Inhibitors |
| General subdivision | pharmacology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HL-60 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukemia, Myeloid, Acute |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukemia, Promyelocytic, Acute |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred NOD |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, SCID |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Oxidoreductases Acting on CH-CH Group Donors |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidines |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | THP-1 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Translocation, Genetic |
| General subdivision | drug effects |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Merz, Claudia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Evans, Laura |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gradl, Stefan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Seidel, Henrik |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Friberg, Anders |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eheim, Ashley |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lejeune, Pascale |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brzezinka, Krzysztof |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zimmermann, Katja |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ferrara, Steven |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Meyer, Hanna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lesche, Ralf |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stoeckigt, Detlef |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bauser, Marcus |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Haegebarth, Andrea |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sykes, David B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Scadden, David T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Losman, Julie-Aurore |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Janzer, Andreas |
| 773 0# - HOST ITEM ENTRY | |
| Title | Leukemia |
| Related parts | vol. 33 |
| -- | no. 10 |
| -- | p. 2403-2415 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/s41375-019-0461-5">https://doi.org/10.1038/s41375-019-0461-5</a> |
| Public note | Available from publisher's website |
No items available.