RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers. (Record no. 28726980)

MARC details
000 -LEADER
fixed length control field 02645 a2200757 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250517232726.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201905s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1476-4679
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1038/s41556-018-0169-1
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Nichols, Robert J
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20190507
245 00 - TITLE STATEMENT
Title RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Nature cell biology
Date of publication, distribution, etc. 09 2018
300 ## - PHYSICAL DESCRIPTION
Extent 1064-1073 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Antineoplastic Agents
General subdivision pharmacology
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biomarkers, Tumor
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Line, Tumor
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Enzyme Inhibitors
General subdivision pharmacology
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Extracellular Signal-Regulated MAP Kinases
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Genetic Predisposition to Disease
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Guanosine Triphosphate
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HEK293 Cells
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice, Inbred BALB C
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice, Nude
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mitogen-Activated Protein Kinase Kinases
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mutation
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neoplasms
General subdivision drug therapy
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neurofibromin 1
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Phenotype
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Tyrosine Phosphatase, Non-Receptor Type 11
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Proto-Oncogene Proteins B-raf
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Proto-Oncogene Proteins p21(ras)
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SOS1 Protein
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Signal Transduction
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Tumor Burden
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Xenograft Model Antitumor Assays
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element raf Kinases
General subdivision metabolism
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Haderk, Franziska
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Stahlhut, Carlos
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schulze, Christopher J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hemmati, Golzar
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wildes, David
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Tzitzilonis, Christos
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mordec, Kasia
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Marquez, Abby
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Romero, Jason
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hsieh, Tientien
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zaman, Aubhishek
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Olivas, Victor
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name McCoach, Caroline
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Blakely, Collin M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wang, Zhengping
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Kiss, Gert
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Koltun, Elena S
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gill, Adrian L
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Singh, Mallika
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Goldsmith, Mark A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Smith, Jacqueline A M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bivona, Trever G
773 0# - HOST ITEM ENTRY
Title Nature cell biology
Related parts vol. 20
-- no. 9
-- p. 1064-1073
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1038/s41556-018-0169-1">https://doi.org/10.1038/s41556-018-0169-1</a>
Public note Available from publisher's website

No items available.