Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates. (Record no. 28064487)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02920 a2200781 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517201054.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201803s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1768-3254 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.ejmech.2018.01.066 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Dias Viegas, Flávia Pereira |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20180321 |
| 245 00 - TITLE STATEMENT | |
| Title | Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | European journal of medicinal chemistry |
| Date of publication, distribution, etc. | Mar 2018 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 48-65 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Acetylcholinesterase |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Alzheimer Disease |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anti-Inflammatory Agents, Non-Steroidal |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cholinesterase Inhibitors |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Donepezil |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dose-Response Relationship, Drug |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Discovery |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hep G2 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hydrazones |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Indans |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Structure |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neuroprotective Agents |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Piperidines |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | de Freitas Silva, Matheus |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Divino da Rocha, Miguel |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Castelli, Maísa Rosa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Riquiel, Mariana Máximo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Machado, Rafael Pereira |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vaz, Sarah Macedo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Simões de Lima, Laís Medeiros |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mancini, Karla Cristine |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marques de Oliveira, Patrícia Cruz |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Morais, Élida Parreira |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gontijo, Vanessa Silva |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | da Silva, Fernanda Motta R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | D'Alincourt da Fonseca Peçanha, Dora |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Castro, Newton Gonçalves |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Neves, Gilda A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Giusti-Paiva, Alexandre |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vilela, Fabiana Cardoso |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Orlandi, Lidiane |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Camps, Ihosvany |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Veloso, Márcia Paranho |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leomil Coelho, Luis Felipe |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ionta, Marisa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ferreira-Silva, Guilherme Álvaro |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pereira, Rodrigo Machado |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dardenne, Laurent E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Guedes, Isabella Alvim |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | de Oliveira Carneiro Junior, Wellerson |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Quaglio Bellozi, Paula Maria |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pinheiro de Oliveira, Antônio Carlos |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ferreira, Fábio Furlan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pruccoli, Letizia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tarozzi, Andrea |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Viegas, Claudio |
| 773 0# - HOST ITEM ENTRY | |
| Title | European journal of medicinal chemistry |
| Related parts | vol. 147 |
| -- | p. 48-65 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.ejmech.2018.01.066">https://doi.org/10.1016/j.ejmech.2018.01.066</a> |
| Public note | Available from publisher's website |
No items available.