Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors. (Record no. 27288284)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01699 a2200469 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517161113.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201711s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1464-3391 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.bmc.2017.06.002 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Yoon, Suyoung |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20171121 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Bioorganic & medicinal chemistry |
| Date of publication, distribution, etc. | 08 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 4145-4152 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Discovery |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Screening Assays, Antitumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leucine-tRNA Ligase |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mass Spectrometry |
| General subdivision | methods |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mechanistic Target of Rapamycin Complex 1 |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phosphorylation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proton Magnetic Resonance Spectroscopy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Ribosomal Protein S6 Kinases |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Sulfonic Acids |
| General subdivision | chemistry |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kim, Jong Hyun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Koh, Yura |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tran, Phuong-Thao |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ann, Jihyae |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yoon, Ina |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jang, Jayun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kim, Won Kyung |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, Sangkook |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, Jiyoun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kim, Sunghoon |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, Jeewoo |
| 773 0# - HOST ITEM ENTRY | |
| Title | Bioorganic & medicinal chemistry |
| Related parts | vol. 25 |
| -- | no. 15 |
| -- | p. 4145-4152 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.bmc.2017.06.002">https://doi.org/10.1016/j.bmc.2017.06.002</a> |
| Public note | Available from publisher's website |
No items available.