The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity. (Record no. 27219216)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02336 a2200721 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517154944.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201708s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1529-2916 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/ni.3766 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Gorman, Jacquelyn A |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20170828 |
| 245 00 - TITLE STATEMENT | |
| Title | The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Nature immunology |
| Date of publication, distribution, etc. | Jul 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 744-752 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adolescent |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adult |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Autoimmune Diseases |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Autoimmunity |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Blotting, Southern |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cardiovirus Infections |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Diabetes Mellitus, Experimental |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Diabetes Mellitus, Type 1 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Encephalomyocarditis virus |
| General subdivision | immunology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetic Predisposition to Disease |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Immunoblotting |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Interferon Type I |
| General subdivision | immunology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Interferon-Induced Helicase, IFIH1 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Middle Aged |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Polymorphism, Single Nucleotide |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Real-Time Polymerase Chain Reaction |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Reverse Transcriptase Polymerase Chain Reaction |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Virus Diseases |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Young Adult |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hundhausen, Christian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Errett, John S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stone, Amy E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Allenspach, Eric J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ge, Yan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Arkatkar, Tanvi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Clough, Courtnee |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dai, Xuezhi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Khim, Socheath |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pestal, Kathleen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liggitt, Denny |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cerosaletti, Karen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stetson, Daniel B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | James, Richard G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Oukka, Mohamed |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Concannon, Patrick |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gale, Michael |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Buckner, Jane H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rawlings, David J |
| 773 0# - HOST ITEM ENTRY | |
| Title | Nature immunology |
| Related parts | vol. 18 |
| -- | no. 7 |
| -- | p. 744-752 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/ni.3766">https://doi.org/10.1038/ni.3766</a> |
| Public note | Available from publisher's website |
No items available.