Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice. (Record no. 27076618)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01857 a2200589 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517150557.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201708s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1476-4687 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1038/nature22038 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Becker, Lindsay A |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20170822 |
| 245 00 - TITLE STATEMENT | |
| Title | Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Nature |
| Date of publication, distribution, etc. | 04 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 367-371 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyotrophic Lateral Sclerosis |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Ataxin-2 |
| General subdivision | deficiency |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Central Nervous System |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cytoplasmic Granules |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | DNA-Binding Proteins |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Disease Progression |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gene Knockdown Techniques |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Longevity |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Knockout |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Transgenic |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Motor Skills |
| General subdivision | physiology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Oligonucleotides, Antisense |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Aggregation, Pathological |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Stress, Physiological |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Survival Analysis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huang, Brenda |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bieri, Gregor |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ma, Rosanna |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Knowles, David A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jafar-Nejad, Paymaan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Messing, James |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kim, Hong Joo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Soriano, Armand |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Auburger, Georg |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pulst, Stefan M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Taylor, J Paul |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rigo, Frank |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gitler, Aaron D |
| 773 0# - HOST ITEM ENTRY | |
| Title | Nature |
| Related parts | vol. 544 |
| -- | no. 7650 |
| -- | p. 367-371 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1038/nature22038">https://doi.org/10.1038/nature22038</a> |
| Public note | Available from publisher's website |
No items available.