Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA). (Record no. 26933043)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01956 a2200565 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517142131.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201704s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/acs.jmedchem.7b00124 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Gopalsamy, Ariamala |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20170424 |
| 245 00 - TITLE STATEMENT | |
| Title | Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA). |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | 04 2017 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 3094-3108 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Disease Models, Animal |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Design |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Endoribonucleases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Enzyme Inhibitors |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Docking Simulation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Muscular Atrophy, Spinal |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Quinazolines |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RNA, Messenger |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Survival of Motor Neuron 2 Protein |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Narayanan, Arjun |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, Shenping |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Parikh, Mihir D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kyne, Robert E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fadeyi, Olugbeminiyi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tones, Michael A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cherry, Jonathan J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nabhan, Joseph F |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | LaRosa, Gregory |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Petersen, Donna N |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Menard, Carol |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Foley, Timothy L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Noell, Stephen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ren, Yong |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Loria, Paula M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Maglich-Goodwin, Jodi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rong, Haojing |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jones, Lyn H |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 60 |
| -- | no. 7 |
| -- | p. 3094-3108 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/acs.jmedchem.7b00124">https://doi.org/10.1021/acs.jmedchem.7b00124</a> |
| Public note | Available from publisher's website |
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