Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer's disease. (Record no. 26370207)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01957 a2200601 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517113115.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201710s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1758-9193 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1186/s13195-016-0199-5 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Blain, Jean-François |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20171016 |
| 245 00 - TITLE STATEMENT | |
| Title | Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer's disease. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Alzheimer's research & therapy |
| Date of publication, distribution, etc. | 08 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 34 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Alzheimer Disease |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid Precursor Protein Secretases |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amyloid beta-Peptides |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Brain |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Evaluation, Preclinical |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HEK293 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | HeLa Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Heterocyclic Compounds, 4 or More Rings |
| General subdivision | pharmacokinetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, 129 Strain |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neocortex |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nootropic Agents |
| General subdivision | pharmacokinetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Presenilin-1 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Wistar |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bursavich, Matthew G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Freeman, Emily A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hrdlicka, Lori A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hodgdon, Hilliary E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Ting |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Costa, Don E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Harrison, Bryce A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kapadnis, Sudarshan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Murphy, Deirdre A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nolan, Scott |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tu, Zhiming |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tang, Cuyue |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Burnett, Duane A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Patzke, Holger |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Koenig, Gerhard |
| 773 0# - HOST ITEM ENTRY | |
| Title | Alzheimer's research & therapy |
| Related parts | vol. 8 |
| -- | p. 34 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1186/s13195-016-0199-5">https://doi.org/10.1186/s13195-016-0199-5</a> |
| Public note | Available from publisher's website |
No items available.