Discovery of 4-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK. (Record no. 26153248)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02455 a2200709 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517102544.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201706s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1464-3405 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.bmcl.2016.06.021 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Laufer, Radoslaw |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20170619 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery of 4-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Bioorganic & medicinal chemistry letters |
| Date of publication, distribution, etc. | 08 2016 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 3562-6 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Agents |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Benzamides |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biological Availability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Cycle Proteins |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Death |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line, Tumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Proliferation |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dose-Response Relationship, Drug |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Discovery |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Screening Assays, Antitumor |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Structure |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Kinase Inhibitors |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Serine-Threonine Kinases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein-Tyrosine Kinases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Triazines |
| General subdivision | administration & dosage |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, Sze-Wan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, Yong |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ng, Grace |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lang, Yunhui |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Feher, Miklos |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brokx, Richard |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Beletskaya, Irina |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hodgson, Richard |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mao, Guodong |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Plotnikova, Olga |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Awrey, Donald E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mason, Jacqueline M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wei, Xin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lin, Dan Chi-Chia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Che, Yi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kiarash, Reza |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Madeira, Brian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Fletcher, Graham C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mak, Tak W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bray, Mark R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pauls, Henry W |
| 773 0# - HOST ITEM ENTRY | |
| Title | Bioorganic & medicinal chemistry letters |
| Related parts | vol. 26 |
| -- | no. 15 |
| -- | p. 3562-6 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.bmcl.2016.06.021">https://doi.org/10.1016/j.bmcl.2016.06.021</a> |
| Public note | Available from publisher's website |
No items available.