Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases. (Record no. 25013409)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01954 a2200553 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250517040400.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201510s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/acs.jmedchem.5b00599 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Farina, Roberta |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20151012 |
| 245 00 - TITLE STATEMENT | |
| Title | Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Jul 2015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 5561-78 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Blood-Brain Barrier |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cholinesterase Inhibitors |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cholinesterases |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Coumarins |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Design |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Inhibitory Concentration 50 |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Madin Darby Canine Kidney Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Docking Simulation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Monoamine Oxidase |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Monoamine Oxidase Inhibitors |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Permeability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Conformation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pisani, Leonardo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Catto, Marco |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nicolotti, Orazio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gadaleta, Domenico |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Denora, Nunzio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Soto-Otero, Ramon |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mendez-Alvarez, Estefania |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Passos, Carolina S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Muncipinto, Giovanni |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Altomare, Cosimo D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nurisso, Alessandra |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Carrupt, Pierre-Alain |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Carotti, Angelo |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 58 |
| -- | no. 14 |
| -- | p. 5561-78 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/acs.jmedchem.5b00599">https://doi.org/10.1021/acs.jmedchem.5b00599</a> |
| Public note | Available from publisher's website |
No items available.