Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent. (Record no. 22943731)

MARC details
000 -LEADER
fixed length control field 02919 a2200841 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250516162022.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201311s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1091-6490
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1073/pnas.1302725110
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Merchant, Mark
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20131104
245 00 - TITLE STATEMENT
Title Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Proceedings of the National Academy of Sciences of the United States of America
Date of publication, distribution, etc. Aug 2013
300 ## - PHYSICAL DESCRIPTION
Extent E2987-96 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Amino Acid Sequence
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Antibodies, Monoclonal
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Antibodies, Monoclonal, Humanized
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Antineoplastic Agents
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Line, Tumor
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Proliferation
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Crystallography, X-Ray
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Drug Design
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hepatocyte Growth Factor
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Immunoglobulin Fab Fragments
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice, Inbred BALB C
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice, Inbred C3H
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice, Nude
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice, SCID
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice, Transgenic
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Models, Molecular
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular Sequence Data
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neoplasms
General subdivision drug therapy
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Binding
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Structure, Tertiary
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Proto-Oncogene Proteins c-met
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Sequence Homology, Amino Acid
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Xenograft Model Antitumor Assays
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ma, Xiaolei
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Maun, Henry R
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zheng, Zhong
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Peng, Jing
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Romero, Mally
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Huang, Arthur
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Yang, Nai-ying
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Nishimura, Merry
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Greve, Joan
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Santell, Lydia
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, Yu-Wen
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Su, Yanli
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Kaufman, Dafna W
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Billeci, Karen L
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mai, Elaine
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Moffat, Barbara
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lim, Amy
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Duenas, Eileen T
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Phillips, Heidi S
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Xiang, Hong
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Young, Judy C
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Vande Woude, George F
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Dennis, Mark S
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Reilly, Dorothea E
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schwall, Ralph H
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Starovasnik, Melissa A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lazarus, Robert A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Yansura, Daniel G
773 0# - HOST ITEM ENTRY
Title Proceedings of the National Academy of Sciences of the United States of America
Related parts vol. 110
-- no. 32
-- p. E2987-96
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1073/pnas.1302725110">https://doi.org/10.1073/pnas.1302725110</a>
Public note Available from publisher's website

No items available.