Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): a potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery. (Record no. 22712954)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02164 a2200601 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516145845.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201312s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1464-3405 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.bmcl.2013.04.012 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Chaturvedula, Prasad V |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20131209 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery of (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide (BMS-742413): a potent human CGRP antagonist with superior safety profile for the treatment of migraine through intranasal delivery. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Bioorganic & medicinal chemistry letters |
| Date of publication, distribution, etc. | Jun 2013 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 3157-61 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Intranasal |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amides |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Caco-2 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Calcitonin Gene-Related Peptide Receptor Antagonists |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Callithrix |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Coronary Vessels |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Evaluation, Preclinical |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Face |
| General subdivision | blood supply |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Indazoles |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Migraine Disorders |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Quinolones |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rabbits |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, Calcitonin Gene-Related Peptide |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Respiratory Mucosa |
| General subdivision | drug effects |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mercer, Stephen E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pin, Sokhom S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thalody, George |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Xu, Cen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Conway, Charlie M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Keavy, Deborah |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Signor, Laura |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cantor, Glenn H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mathias, Neil |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Moench, Paul |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Denton, Rex |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Macci, Robert |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schartman, Richard |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Whiterock, Valerie |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Davis, Carl |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Macor, John E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dubowchik, Gene M |
| 773 0# - HOST ITEM ENTRY | |
| Title | Bioorganic & medicinal chemistry letters |
| Related parts | vol. 23 |
| -- | no. 11 |
| -- | p. 3157-61 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.bmcl.2013.04.012">https://doi.org/10.1016/j.bmcl.2013.04.012</a> |
| Public note | Available from publisher's website |
No items available.