SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors. (Record no. 22241097)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02859 a2200913 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516120929.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201305s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1464-3405 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1016/j.bmcl.2012.10.007 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Forsyth, Timothy |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20130520 |
| 245 00 - TITLE STATEMENT | |
| Title | SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Bioorganic & medicinal chemistry letters |
| Date of publication, distribution, etc. | Dec 2012 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 7653-8 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Agents |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Apoptosis |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Proliferation |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Crystallography, X-Ray |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dose-Response Relationship, Drug |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Haplorhini |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | High-Throughput Screening Assays |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Janus Kinase 2 |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Nude |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Molecular Structure |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neoplasms, Experimental |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proline |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Kinase Inhibitors |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidines |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Xenograft Model Antitumor Assays |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kearney, Patrick C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kim, Byung Gyu |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Johnson, Henry W B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aay, Naing |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Arcalas, Arlyn |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brown, David S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chan, Vicky |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chen, Jeff |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Du, Hongwang |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Epshteyn, Sergey |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Galan, Adam A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Huynh, Tai P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ibrahim, Mohamed A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kane, Brian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Koltun, Elena S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mann, Grace |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Meyr, Lisa E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lee, Matthew S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lewis, Gary L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Noguchi, Robin T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pack, Michael |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ridgway, Brian H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shi, Xian |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Takeuchi, Craig S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zu, Peiwen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leahy, James W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nuss, John M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Aoyama, Ron |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Engst, Stefan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gendreau, Steven B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kassees, Robert |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Li, Jia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lin, Shwu-Hwa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Martini, Jean-Francois |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stout, Thomas |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tong, Philip |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Woolfrey, John |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhang, Wentao |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Yu, Peiwen |
| 773 0# - HOST ITEM ENTRY | |
| Title | Bioorganic & medicinal chemistry letters |
| Related parts | vol. 22 |
| -- | no. 24 |
| -- | p. 7653-8 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1016/j.bmcl.2012.10.007">https://doi.org/10.1016/j.bmcl.2012.10.007</a> |
| Public note | Available from publisher's website |
No items available.