Significant species difference in amide hydrolysis of GDC-0834, a novel potent and selective Bruton's tyrosine kinase inhibitor. (Record no. 20994893)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02299 a2200709 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516044904.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201203s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1521-009X |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1124/dmd.111.040840 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Liu, Lichuan |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20120329 |
| 245 00 - TITLE STATEMENT | |
| Title | Significant species difference in amide hydrolysis of GDC-0834, a novel potent and selective Bruton's tyrosine kinase inhibitor. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Drug metabolism and disposition: the biological fate of chemicals |
| Date of publication, distribution, etc. | Oct 2011 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1840-9 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Agammaglobulinaemia Tyrosine Kinase |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Amides |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cells, Cultured |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Clinical Trials, Phase I as Topic |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Double-Blind Method |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hepatocytes |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hydrolysis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Macaca fascicularis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Microsomes, Liver |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Kinase Inhibitors |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein-Tyrosine Kinases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidinones |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Randomized Controlled Trials as Topic |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Species Specificity |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Thiophenes |
| General subdivision | metabolism |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Halladay, Jason S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Shin, Young |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wong, Susan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Coraggio, Melis |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | La, Hank |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Baumgardner, Matthew |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Le, Hoa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gopaul, Sashi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Boggs, Jason |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kuebler, Peter |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Davis, John C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liao, X Charlene |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lubach, Joseph W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Deese, Alan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sowell, C Gregory |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Currie, Kevin S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Young, Wendy B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Khojasteh, S Cyrus |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hop, Cornelis E C A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wong, Harvey |
| 773 0# - HOST ITEM ENTRY | |
| Title | Drug metabolism and disposition: the biological fate of chemicals |
| Related parts | vol. 39 |
| -- | no. 10 |
| -- | p. 1840-9 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1124/dmd.111.040840">https://doi.org/10.1124/dmd.111.040840</a> |
| Public note | Available from publisher's website |
No items available.