Preclinical species and human disposition of PF-04971729, a selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus. (Record no. 20944565)
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000 -LEADER | |
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fixed length control field | 02242 a2200637 4500 |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20250516043201.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 201202s 0 0 eng d |
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
International Standard Serial Number | 1521-009X |
024 7# - OTHER STANDARD IDENTIFIER | |
Standard number or code | 10.1124/dmd.111.040675 |
Source of number or code | doi |
040 ## - CATALOGING SOURCE | |
Original cataloging agency | NLM |
Language of cataloging | eng |
Transcribing agency | NLM |
100 1# - MAIN ENTRY--PERSONAL NAME | |
Personal name | Kalgutkar, Amit S |
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
Date of production, publication, distribution, manufacture, or copyright notice | 20120227 |
245 00 - TITLE STATEMENT | |
Title | Preclinical species and human disposition of PF-04971729, a selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus. |
Medium | [electronic resource] |
260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
Name of publisher, distributor, etc. | Drug metabolism and disposition: the biological fate of chemicals |
Date of publication, distribution, etc. | Sep 2011 |
300 ## - PHYSICAL DESCRIPTION | |
Extent | 1609-19 p. |
Other physical details | digital |
500 ## - GENERAL NOTE | |
General note | Publication Type: Journal Article; Randomized Controlled Trial |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Administration, Oral |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Adult |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Animals |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Biological Availability |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Biotransformation |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Bridged Bicyclo Compounds, Heterocyclic |
General subdivision | pharmacokinetics |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Caco-2 Cells |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Cross-Over Studies |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Cytochrome P-450 Enzyme Inhibitors |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Cytochrome P-450 Enzyme System |
General subdivision | metabolism |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Dogs |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Drug Evaluation, Preclinical |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Female |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Glucuronosyltransferase |
General subdivision | metabolism |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | HEK293 Cells |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Hepatocytes |
General subdivision | drug effects |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Humans |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Intestinal Absorption |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Male |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Microsomes, Liver |
General subdivision | enzymology |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Middle Aged |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Protein Binding |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Rats |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Rats, Sprague-Dawley |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Sodium-Glucose Transport Proteins |
General subdivision | antagonists & inhibitors |
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical term or geographic name entry element | Young Adult |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Tugnait, Meera |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Zhu, Tong |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Kimoto, Emi |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Miao, Zhuang |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Mascitti, Vincent |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Yang, Xin |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Tan, Beijing |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Walsky, Robert L |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Chupka, Jonathan |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Feng, Bo |
700 1# - ADDED ENTRY--PERSONAL NAME | |
Personal name | Robinson, Ralph P |
773 0# - HOST ITEM ENTRY | |
Title | Drug metabolism and disposition: the biological fate of chemicals |
Related parts | vol. 39 |
-- | no. 9 |
-- | p. 1609-19 |
856 40 - ELECTRONIC LOCATION AND ACCESS | |
Uniform Resource Identifier | <a href="https://doi.org/10.1124/dmd.111.040675">https://doi.org/10.1124/dmd.111.040675</a> |
Public note | Available from publisher's website |
No items available.