Discovery of 1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone (GSK163090), a Potent, selective, and orally active 5-HT1A/B/D receptor antagonist. (Record no. 20352743)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01913 a2200565 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250516011959.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201404s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1520-4804 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm100714c |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Leslie, Colin P |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20140415 |
| 245 00 - TITLE STATEMENT | |
| Title | Discovery of 1-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone (GSK163090), a Potent, selective, and orally active 5-HT1A/B/D receptor antagonist. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Dec 2010 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 8228-40 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CHO Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chromatography, Liquid |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cricetulus |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Discovery |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Imidazoles |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Magnetic Resonance Spectroscopy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Quinolines |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, Serotonin |
| General subdivision | classification |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Serotonin Antagonists |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Tandem Mass Spectrometry |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Biagetti, Matteo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bison, Silvia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bromidge, Steven M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Di Fabio, Romano |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Donati, Daniele |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Falchi, Alessandro |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Garnier, Martine J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jaxa-Chamiec, Albert |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Manchee, Gary |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Merlo, Giancarlo |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pizzi, Domenica A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stasi, Luigi P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tibasco, Jessica |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vong, Antonio |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ward, Simon E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zonzini, Laura |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 53 |
| -- | no. 23 |
| -- | p. 8228-40 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm100714c">https://doi.org/10.1021/jm100714c</a> |
| Public note | Available from publisher's website |
No items available.