The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane. (Record no. 19843040)

MARC details
000 -LEADER
fixed length control field 02123 a2200589 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250515224030.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 201103s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1476-5403
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1038/cdd.2010.63
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Berndt, N
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20110321
245 00 - TITLE STATEMENT
Title The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Cell death and differentiation
Date of publication, distribution, etc. Nov 2010
300 ## - PHYSICAL DESCRIPTION
Extent 1795-804 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article; Research Support, N.I.H., Extramural
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element 3-Phosphoinositide-Dependent Protein Kinases
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Acenaphthenes
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Apoptosis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Line, Tumor
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Membrane
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Epidermal Growth Factor
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Fluorescent Antibody Technique
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Gene Amplification
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Intracellular Signaling Peptides and Proteins
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Magnetic Resonance Spectroscopy
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Membrane Proteins
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Phosphoproteins
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Phosphorylation
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Polymerase Chain Reaction
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Serine-Threonine Kinases
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Structure, Tertiary
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Proto-Oncogene Proteins c-akt
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Ribonucleotides
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Signal Transduction
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Surface Plasmon Resonance
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element TOR Serine-Threonine Kinases
General subdivision metabolism
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Yang, H
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Trinczek, B
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Betzi, S
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, Z
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wu, B
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lawrence, N J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Pellecchia, M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schönbrunn, E
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Cheng, J Q
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sebti, S M
773 0# - HOST ITEM ENTRY
Title Cell death and differentiation
Related parts vol. 17
-- no. 11
-- p. 1795-804
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1038/cdd.2010.63">https://doi.org/10.1038/cdd.2010.63</a>
Public note Available from publisher's website

No items available.