High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response. (Record no. 18836735)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02528 a2200697 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250515170535.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200909s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1528-0020 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1182/blood-2008-10-186536 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Remke, Marc |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20090921 |
| 245 00 - TITLE STATEMENT | |
| Title | High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Blood |
| Date of publication, distribution, etc. | Jul 2009 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1053-62 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adolescent |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antineoplastic Combined Chemotherapy Protocols |
| General subdivision | therapeutic use |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Child |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Child, Preschool |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chromosome Deletion |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Chromosomes, Human, Pair 6 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Comparative Genomic Hybridization |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cyclin-Dependent Kinase Inhibitor p27 |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Gene Dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Intracellular Signaling Peptides and Proteins |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Multicenter Studies as Topic |
| General subdivision | statistics & numerical data |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Neoplasm Proteins |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phosphatidylinositol 3-Kinases |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Prognosis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Proto-Oncogene Proteins c-akt |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptor, Notch1 |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Signal Transduction |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Transforming Growth Factor beta |
| General subdivision | genetics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Treatment Outcome |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pfister, Stefan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kox, Corinne |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Toedt, Grischa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Becker, Natalia |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Benner, Axel |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Werft, Wiebke |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Breit, Stephen |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liu, Shuangyou |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Engel, Felix |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wittmann, Andrea |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zimmermann, Martin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stanulla, Martin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schrappe, Martin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ludwig, Wolf-Dieter |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bartram, Claus R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Radlwimmer, Bernhard |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Muckenthaler, Martina U |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lichter, Peter |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kulozik, Andreas E |
| 773 0# - HOST ITEM ENTRY | |
| Title | Blood |
| Related parts | vol. 114 |
| -- | no. 5 |
| -- | p. 1053-62 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1182/blood-2008-10-186536">https://doi.org/10.1182/blood-2008-10-186536</a> |
| Public note | Available from publisher's website |
No items available.