Discovery of N1-(6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a potent, selective, and orally active 5-HT(6) receptor agonist. (Record no. 17468925)

MARC details
000 -LEADER
fixed length control field 02201 a2200685 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250515092116.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200801s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0022-2623
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1021/jm070521y
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Cole, Derek C
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20080108
245 00 - TITLE STATEMENT
Title Discovery of N1-(6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a potent, selective, and orally active 5-HT(6) receptor agonist.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Journal of medicinal chemistry
Date of publication, distribution, etc. Nov 2007
300 ## - PHYSICAL DESCRIPTION
Extent 5535-8 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article; Research Support, Non-U.S. Gov't
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Administration, Oral
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biological Availability
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CHO Cells
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cricetinae
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cricetulus
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Dogs
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Frontal Lobe
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Haplorhini
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element In Vitro Techniques
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Microdialysis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Microsomes, Liver
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Radioligand Assay
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Rats
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Receptors, Serotonin
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Serotonin Receptor Agonists
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Solubility
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Structure-Activity Relationship
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Thiazoles
General subdivision chemistry
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Tryptamines
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element gamma-Aminobutyric Acid
General subdivision metabolism
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Stock, Joseph R
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lennox, William J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bernotas, Ronald C
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ellingboe, John W
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Boikess, Steve
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Coupet, Joseph
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Smith, Deborah L
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Leung, Louis
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, Guo-Ming
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Feng, Xidong
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Kelly, Michael F
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Galante, Rocco
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Huang, Pingzhong
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Dawson, Lee A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Marquis, Karen
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Rosenzweig-Lipson, Sharon
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Beyer, Chad E
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schechter, Lee E
773 0# - HOST ITEM ENTRY
Title Journal of medicinal chemistry
Related parts vol. 50
-- no. 23
-- p. 5535-8
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1021/jm070521y">https://doi.org/10.1021/jm070521y</a>
Public note Available from publisher's website

No items available.