Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. (Record no. 17460333)

MARC details
000 -LEADER
fixed length control field 02200 a2200613 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250515091822.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200711s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0027-8424
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1073/pnas.0708285104
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name DiFiglia, M
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20071127
245 00 - TITLE STATEMENT
Title Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Proceedings of the National Academy of Sciences of the United States of America
Date of publication, distribution, etc. Oct 2007
300 ## - PHYSICAL DESCRIPTION
Extent 17204-9 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Behavior, Animal
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cerebral Cortex
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cholesterol
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Dependovirus
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Disease Models, Animal
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Gene Silencing
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Genetic Therapy
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Huntingtin Protein
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Huntington Disease
General subdivision pathology
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Injections
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Intranuclear Inclusion Bodies
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Motor Neuron Disease
General subdivision pathology
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mutant Proteins
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neostriatum
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Nerve Tissue Proteins
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neurons
General subdivision pathology
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neuropil Threads
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Nuclear Proteins
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element RNA, Small Interfering
General subdivision pharmacology
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sena-Esteves, M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Chase, K
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sapp, E
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Pfister, E
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sass, M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Yoder, J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Reeves, P
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Pandey, R K
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Rajeev, K G
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Manoharan, M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sah, D W Y
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zamore, P D
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Aronin, N
773 0# - HOST ITEM ENTRY
Title Proceedings of the National Academy of Sciences of the United States of America
Related parts vol. 104
-- no. 43
-- p. 17204-9
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1073/pnas.0708285104">https://doi.org/10.1073/pnas.0708285104</a>
Public note Available from publisher's website

No items available.