Macrocyclic ureas as potent and selective Chk1 inhibitors: an improved synthesis, kinome profiling, structure-activity relationships, and preliminary pharmacokinetics. (Record no. 17456531)

MARC details
000 -LEADER
fixed length control field 01550 a2200433 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250515091634.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200803s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1464-3405
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.bmcl.2007.09.063
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Tao, Zhi-Fu
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20080303
245 00 - TITLE STATEMENT
Title Macrocyclic ureas as potent and selective Chk1 inhibitors: an improved synthesis, kinome profiling, structure-activity relationships, and preliminary pharmacokinetics.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Bioorganic & medicinal chemistry letters
Date of publication, distribution, etc. Dec 2007
300 ## - PHYSICAL DESCRIPTION
Extent 6593-601 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Comparative Study; Journal Article
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Catalysis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Checkpoint Kinase 1
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element HeLa Cells
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Macrocyclic Compounds
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Kinase Inhibitors
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Kinases
General subdivision pharmacokinetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Structure-Activity Relationship
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Urea
General subdivision chemical synthesis
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Chen, Zehan
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bui, Mai-Ha
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Kovar, Peter
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Johnson, Eric
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bouska, Jennifer
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Zhang, Haiying
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Rosenberg, Saul
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sowin, Thomas
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lin, Nan-Horng
773 0# - HOST ITEM ENTRY
Title Bioorganic & medicinal chemistry letters
Related parts vol. 17
-- no. 23
-- p. 6593-601
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1016/j.bmcl.2007.09.063">https://doi.org/10.1016/j.bmcl.2007.09.063</a>
Public note Available from publisher's website

No items available.