Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2(1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception. (Record no. 15378178)

MARC details
000 -LEADER
fixed length control field 01949 a2200481 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250514215808.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200507s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0022-3565
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1124/jpet.104.079285
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Sivarao, Digavalli V
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20050705
245 00 - TITLE STATEMENT
Title Effect of 4-(5-chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2(1H)-one (BMS-223131), a novel opener of large conductance Ca2+-activated K+ (maxi-K) channels on normal and stress-aggravated colonic motility and visceral nociception.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. The Journal of pharmacology and experimental therapeutics
Date of publication, distribution, etc. May 2005
300 ## - PHYSICAL DESCRIPTION
Extent 840-7 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Comparative Study; Journal Article
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Blood Pressure
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Colon
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Dose-Response Relationship, Drug
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Gastrointestinal Motility
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Ion Channel Gating
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Large-Conductance Calcium-Activated Potassium Channels
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Pain Measurement
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Potassium Channels, Calcium-Activated
General subdivision agonists
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Quinolines
General subdivision administration & dosage
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Quinolones
General subdivision administration & dosage
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Rats
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Rats, Wistar
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Stress, Physiological
General subdivision drug therapy
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Viscera
General subdivision drug effects
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Newberry, Kimberly
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Langdon, Shaun
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lee, Alicia V
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hewawasam, Piyasena
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Plym, Mary Jane
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Signor, Laura
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Myers, Robert
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lodge, Nicholas J
773 0# - HOST ITEM ENTRY
Title The Journal of pharmacology and experimental therapeutics
Related parts vol. 313
-- no. 2
-- p. 840-7
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1124/jpet.104.079285">https://doi.org/10.1124/jpet.104.079285</a>
Public note Available from publisher's website

No items available.