An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties. (Record no. 15224633)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01753 a2200529 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250514210637.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200501s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0022-2623 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm040863t |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Chambers, Mark S |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20050103 |
| 245 00 - TITLE STATEMENT | |
| Title | An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Nov 2004 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 5829-32 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Binding Sites |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biological Availability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cognition |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | GABA-A Receptor Agonists |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Isoxazoles |
| General subdivision | adverse effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Maze Learning |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Nootropic Agents |
| General subdivision | adverse effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Patch-Clamp Techniques |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Subunits |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Radioligand Assay |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, GABA-A |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Triazines |
| General subdivision | adverse effects |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Atack, John R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Carling, Robert W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Collinson, Neil |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Cook, Susan M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dawson, Gerard R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ferris, Pushpindar |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hobbs, Sarah C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | O'connor, Desmond |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Marshall, George |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rycroft, W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Macleod, Angus M |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 47 |
| -- | no. 24 |
| -- | p. 5829-32 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm040863t">https://doi.org/10.1021/jm040863t</a> |
| Public note | Available from publisher's website |
No items available.