Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding site. (Record no. 14920025)

MARC details
000 -LEADER
fixed length control field 02185 a2200661 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250514192522.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200408s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0022-2623
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1021/jm0407613
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Street, Leslie J
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 20040802
245 00 - TITLE STATEMENT
Title Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and analogues as subtype-selective inverse agonists for the GABA(A)alpha5 benzodiazepine binding site.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Journal of medicinal chemistry
Date of publication, distribution, etc. Jul 2004
300 ## - PHYSICAL DESCRIPTION
Extent 3642-57 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Administration, Oral
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Binding Sites
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biological Availability
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Line
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Female
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element GABA-A Receptor Agonists
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Isoxazoles
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Maze Learning
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Oocytes
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Patch-Clamp Techniques
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Phthalazines
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Subunits
General subdivision agonists
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Radioligand Assay
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Rats
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Structure-Activity Relationship
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Triazoles
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Xenopus laevis
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sternfeld, Francine
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jelley, Richard A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Reeve, Austin J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Carling, Robert W
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Moore, Kevin W
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name McKernan, Ruth M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sohal, Bindi
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Cook, Susan
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Pike, Andrew
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Dawson, Gerard R
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bromidge, Frances A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wafford, Keith A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Seabrook, Guy R
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Thompson, Sally A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Marshall, George
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Pillai, Goplan V
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Castro, José L
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Atack, John R
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name MacLeod, Angus M
773 0# - HOST ITEM ENTRY
Title Journal of medicinal chemistry
Related parts vol. 47
-- no. 14
-- p. 3642-57
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1021/jm0407613">https://doi.org/10.1021/jm0407613</a>
Public note Available from publisher's website

No items available.