Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial. (Record no. 11301543)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02498 a2200733 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250514001056.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200106s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0006-4971 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1182/blood.v97.11.3361 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Karp, J E |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20010628 |
| 245 00 - TITLE STATEMENT | |
| Title | Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Blood |
| Date of publication, distribution, etc. | Jun 2001 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 3361-9 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adult |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aged |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Alkyl and Aryl Transferases |
| General subdivision | antagonists & inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bone Marrow |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cohort Studies |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dose-Response Relationship, Drug |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Enzyme Activation |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Enzyme Inhibitors |
| General subdivision | adverse effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Farnesyltranstransferase |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genes, ras |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukemia, Myelogenous, Chronic, BCR-ABL Positive |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Leukemia, Myeloid, Acute |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Middle Aged |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mitogen-Activated Protein Kinase 1 |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mitogen-Activated Protein Kinase 3 |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mitogen-Activated Protein Kinases |
| General subdivision | metabolism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Phosphorylation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Protein Prenylation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Quinolones |
| General subdivision | adverse effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Recurrence |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Remission Induction |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Treatment Outcome |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lancet, J E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kaufmann, S H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | End, D W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wright, J J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bol, K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Horak, I |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tidwell, M L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liesveld, J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kottke, T J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ange, D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Buddharaju, L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gojo, I |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Highsmith, W E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Belly, R T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hohl, R J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rybak, M E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thibault, A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rosenblatt, J |
| 773 0# - HOST ITEM ENTRY | |
| Title | Blood |
| Related parts | vol. 97 |
| -- | no. 11 |
| -- | p. 3361-9 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1182/blood.v97.11.3361">https://doi.org/10.1182/blood.v97.11.3361</a> |
| Public note | Available from publisher's website |
No items available.