In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia. (Record no. 10843710)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 01988 a2200637 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250513214002.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 200008s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0022-2623 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm990612y |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Barrow, J C |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20000803 |
| 245 00 - TITLE STATEMENT | |
| Title | In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Jul 2000 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 2703-18 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adrenergic alpha-Antagonists |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Biological Availability |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Caco-2 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Crystallography, X-Ray |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Prostatic Hyperplasia |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pyrimidinones |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Radioligand Assay |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats, Sprague-Dawley |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, Adrenergic, alpha-1 |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nantermet, P G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Selnick, H G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Glass, K L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rittle, K E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gilbert, K F |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Steele, T G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Homnick, C F |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Freidinger, R M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ransom, R W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kling, P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Reiss, D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Broten, T P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schorn, T W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chang, R S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | O'Malley, S S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Olah, T V |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ellis, J D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Barrish, A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kassahun, K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leppert, P |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nagarathnam, D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Forray, C |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 43 |
| -- | no. 14 |
| -- | p. 2703-18 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm990612y">https://doi.org/10.1021/jm990612y</a> |
| Public note | Available from publisher's website |
No items available.