Pharmacology of LY315920/S-5920, [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate, a potent and selective secretory phospholipase A2 inhibitor: A new class of anti-inflammatory drugs, SPI.
Snyder, D W
Pharmacology of LY315920/S-5920, [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate, a potent and selective secretory phospholipase A2 inhibitor: A new class of anti-inflammatory drugs, SPI. [electronic resource] - The Journal of pharmacology and experimental therapeutics Mar 1999 - 1117-24 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3565
Acetates--pharmacology
Animals
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Arachidonic Acid--pharmacology
Cell Line
Cloning, Molecular
Cricetinae
Group II Phospholipases A2
Guinea Pigs
Humans
Indoles--pharmacology
Keto Acids
Male
Mesocricetus
Mice
Mice, Transgenic
Muscle, Smooth--drug effects
Phospholipases A--antagonists & inhibitors
Phospholipases A2
Pleura--drug effects
Rabbits
Rats
Recombinant Proteins--biosynthesis
Thromboxane A2--biosynthesis
Pharmacology of LY315920/S-5920, [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate, a potent and selective secretory phospholipase A2 inhibitor: A new class of anti-inflammatory drugs, SPI. [electronic resource] - The Journal of pharmacology and experimental therapeutics Mar 1999 - 1117-24 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0022-3565
Acetates--pharmacology
Animals
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Arachidonic Acid--pharmacology
Cell Line
Cloning, Molecular
Cricetinae
Group II Phospholipases A2
Guinea Pigs
Humans
Indoles--pharmacology
Keto Acids
Male
Mesocricetus
Mice
Mice, Transgenic
Muscle, Smooth--drug effects
Phospholipases A--antagonists & inhibitors
Phospholipases A2
Pleura--drug effects
Rabbits
Rats
Recombinant Proteins--biosynthesis
Thromboxane A2--biosynthesis