Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway.

You, M

Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway. [electronic resource] - Molecular and cellular biology Mar 1999 - 2416-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0270-7306

10.1128/MCB.19.3.2416 doi


Animals
Caspase 1--metabolism
Cell Line
DNA-Binding Proteins--genetics
Enzyme Induction
Fibroblasts--cytology
Humans
Interferon-alpha--metabolism
Interferon-gamma--metabolism
Intracellular Signaling Peptides and Proteins
Janus Kinase 1
Membrane Proteins
Mice
Mutagenesis
Phenotype
Phosphorylation
Protein Tyrosine Phosphatase, Non-Receptor Type 11
Protein Tyrosine Phosphatase, Non-Receptor Type 6
Protein Tyrosine Phosphatases--genetics
Protein-Tyrosine Kinases--metabolism
Receptor, Interferon alpha-beta
Receptors, Interferon--metabolism
SH2 Domain-Containing Protein Tyrosine Phosphatases
STAT1 Transcription Factor
STAT2 Transcription Factor
Signal Transduction
Trans-Activators--genetics
Interferon gamma Receptor