Inhibition of cruzipain visualized in a fluorescence quenched solid-phase inhibitor library assay. D-amino acid inhibitors for cruzipain, cathepsin B and cathepsin L.

Meldal, M

Inhibition of cruzipain visualized in a fluorescence quenched solid-phase inhibitor library assay. D-amino acid inhibitors for cruzipain, cathepsin B and cathepsin L. [electronic resource] - Journal of peptide science : an official publication of the European Peptide Society Apr 1998 - 83-91 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1075-2617

10.1002/(sici)1099-1387(199804)4:2<83::aid-psc124>3.0.co;2-z doi


Amino Acids--pharmacology
Animals
Binding Sites--physiology
Binding, Competitive
Cathepsin B--metabolism
Cathepsin L
Cathepsins--metabolism
Cysteine Endopeptidases--metabolism
Endopeptidases
Enzyme Inhibitors--pharmacology
Fluorescent Dyes--metabolism
Humans
Kallikreins--metabolism
Kinetics
Mammals
Models, Molecular
Peptide Library
Peptides--chemical synthesis
Protein Conformation
Protozoan Proteins--metabolism
Substrate Specificity
Trypanosoma cruzi--enzymology