The multiple endocrine neoplasia type 2B point mutation alters long-term regulation and enhances the transforming capacity of the epidermal growth factor receptor.

Pandit, S D

The multiple endocrine neoplasia type 2B point mutation alters long-term regulation and enhances the transforming capacity of the epidermal growth factor receptor. [electronic resource] - The Journal of biological chemistry Mar 1996 - 5850-8 p. digital

Publication Type: Comparative Study; Journal Article

0021-9258

10.1074/jbc.271.10.5850 doi


3T3 Cells
Amino Acid Sequence
Animals
Base Sequence
Cell Division--drug effects
Cell Line
Cell Transformation, Neoplastic
DNA Primers
Down-Regulation
Drosophila Proteins
Epidermal Growth Factor--metabolism
ErbB Receptors--biosynthesis
Gene Expression Regulation, Neoplastic
Gene Library
Humans
Kinetics
Mice
Molecular Sequence Data
Multiple Endocrine Neoplasia Type 2b--genetics
Mutagenesis, Site-Directed
Peptides--chemical synthesis
Phosphorylation
Plasmids
Point Mutation
Proto-Oncogene Mas
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-ret
Proto-Oncogenes
Receptor Protein-Tyrosine Kinases--genetics
Recombinant Proteins--biosynthesis
Substrate Specificity
Tumor Cells, Cultured