Artificial duplication of the R67 dihydrofolate reductase gene to create protein asymmetry. Effects on protein activity and folding.

Zhuang, P

Artificial duplication of the R67 dihydrofolate reductase gene to create protein asymmetry. Effects on protein activity and folding. [electronic resource] - The Journal of biological chemistry Oct 1993 - 22672-9 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0021-9258


Amino Acid Sequence
Base Sequence
Calorimetry, Differential Scanning
Circular Dichroism
Cloning, Molecular
Enzyme Stability
Escherichia coli--enzymology
Genes, Bacterial
Kinetics
Macromolecular Substances
Mathematics
Models, Structural
Molecular Sequence Data
Multigene Family
Protein Conformation
Protein Denaturation
Protein Folding
Protein Structure, Secondary
R Factors
Recombinant Proteins--chemistry
Restriction Mapping
Tetrahydrofolate Dehydrogenase--chemistry