6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding site and modelling of substrate binding.
Bürgisser, D M
6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding site and modelling of substrate binding. [electronic resource] - Journal of molecular biology Oct 1995 - 358-69 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0022-2836
10.1006/jmbi.1995.0558 doi
Alcohol Oxidoreductases--chemistry
Amino Acid Sequence
Animals
Apoenzymes--chemistry
Base Sequence
Binding Sites
DNA Primers
Escherichia coli
Humans
Macromolecular Substances
Magnesium--analysis
Models, Molecular
Molecular Sequence Data
Mutagenesis, Site-Directed
Phosphorus-Oxygen Lyases
Point Mutation
Protein Structure, Secondary
Rats
Recombinant Fusion Proteins--biosynthesis
Recombinant Proteins--chemistry
Salmon
Sequence Homology, Amino Acid
Spectrophotometry, Atomic
Zinc--metabolism
6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding site and modelling of substrate binding. [electronic resource] - Journal of molecular biology Oct 1995 - 358-69 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
0022-2836
10.1006/jmbi.1995.0558 doi
Alcohol Oxidoreductases--chemistry
Amino Acid Sequence
Animals
Apoenzymes--chemistry
Base Sequence
Binding Sites
DNA Primers
Escherichia coli
Humans
Macromolecular Substances
Magnesium--analysis
Models, Molecular
Molecular Sequence Data
Mutagenesis, Site-Directed
Phosphorus-Oxygen Lyases
Point Mutation
Protein Structure, Secondary
Rats
Recombinant Fusion Proteins--biosynthesis
Recombinant Proteins--chemistry
Salmon
Sequence Homology, Amino Acid
Spectrophotometry, Atomic
Zinc--metabolism