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Abedi, Marjan

Iron protects childhood acute lymphoblastic leukemia cells from methotrexate cytotoxicity. [electronic resource] - Cancer medicine 05 2020 - 3537-3550 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

ISSN: 2045-7634

Standard No.: 10.1002/cam4.2982 doi

Subjects--Topical Terms:
Acetylcysteine--pharmacology
Bone Marrow--metabolism
Cell Line, Tumor
Cell Survival
Child
Child, Preschool
Deferasirox--pharmacology
Drug Resistance, Neoplasm--drug effects
Female
Ferric Compounds--pharmacology
Free Radical Scavengers--pharmacology
Humans
Infant
Inhibitory Concentration 50
Iron--metabolism
Iron Chelating Agents--pharmacology
Male
Methotrexate--pharmacology
Multidrug Resistance-Associated Proteins--genetics
NF-E2-Related Factor 2--genetics
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Proto-Oncogene Proteins c-bcl-2--genetics
Quaternary Ammonium Compounds--pharmacology
RNA, Messenger--metabolism
Reactive Oxygen Species
Superoxide Dismutase--genetics
Transcriptome
Up-Regulation