A study on the mechanism of rapamycin mediating the sensitivity of pancreatic cancer cells to cisplatin through PI3K/AKT/mTOR signaling pathway.

Li, Baoyu

A study on the mechanism of rapamycin mediating the sensitivity of pancreatic cancer cells to cisplatin through PI3K/AKT/mTOR signaling pathway. [electronic resource] - Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 739-745 p. digital

Publication Type: Journal Article

2241-6293


Animals
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Apoptosis--drug effects
Autophagy--genetics
Cell Line, Tumor
Cell Proliferation--drug effects
Cisplatin--pharmacology
Drug Resistance, Neoplasm--drug effects
Gene Expression Regulation, Neoplastic
Humans
Pancreatic Neoplasms--drug therapy
Phosphatidylinositol 3-Kinases--genetics
Phosphorylation--drug effects
Proto-Oncogene Proteins c-akt--genetics
Signal Transduction--drug effects
Sirolimus--pharmacology
TOR Serine-Threonine Kinases--genetics