NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report.
van der Heijden, Thomas
NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology 08 2017 - 1457-1461 p. digital
Publication Type: Journal Article
1524-4636
10.1161/ATVBAHA.117.309575 doi
Animals
Anti-Inflammatory Agents--pharmacology
Apolipoproteins E--deficiency
Atherosclerosis--genetics
Carotid Arteries--drug effects
Carotid Artery Diseases--genetics
Cells, Cultured
Cholesterol--pharmacology
Crystallization
Dendritic Cells--drug effects
Diet, Western
Disease Models, Animal
Female
Furans
Genetic Predisposition to Disease
Heterocyclic Compounds, 4 or More Rings--pharmacology
Indenes
Inflammasomes--antagonists & inhibitors
Intercellular Adhesion Molecule-1--genetics
Interleukin-1beta--metabolism
Lipopolysaccharides--pharmacology
Macrophages--drug effects
Mice, Inbred C57BL
Mice, Knockout
NLR Family, Pyrin Domain-Containing 3 Protein--antagonists & inhibitors
Necrosis
Phenotype
Plaque, Atherosclerotic
RNA, Messenger--genetics
Signal Transduction--drug effects
Sulfonamides
Sulfones--pharmacology
Time Factors
Vascular Cell Adhesion Molecule-1--genetics
NLRP3 Inflammasome Inhibition by MCC950 Reduces Atherosclerotic Lesion Development in Apolipoprotein E-Deficient Mice-Brief Report. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology 08 2017 - 1457-1461 p. digital
Publication Type: Journal Article
1524-4636
10.1161/ATVBAHA.117.309575 doi
Animals
Anti-Inflammatory Agents--pharmacology
Apolipoproteins E--deficiency
Atherosclerosis--genetics
Carotid Arteries--drug effects
Carotid Artery Diseases--genetics
Cells, Cultured
Cholesterol--pharmacology
Crystallization
Dendritic Cells--drug effects
Diet, Western
Disease Models, Animal
Female
Furans
Genetic Predisposition to Disease
Heterocyclic Compounds, 4 or More Rings--pharmacology
Indenes
Inflammasomes--antagonists & inhibitors
Intercellular Adhesion Molecule-1--genetics
Interleukin-1beta--metabolism
Lipopolysaccharides--pharmacology
Macrophages--drug effects
Mice, Inbred C57BL
Mice, Knockout
NLR Family, Pyrin Domain-Containing 3 Protein--antagonists & inhibitors
Necrosis
Phenotype
Plaque, Atherosclerotic
RNA, Messenger--genetics
Signal Transduction--drug effects
Sulfonamides
Sulfones--pharmacology
Time Factors
Vascular Cell Adhesion Molecule-1--genetics