M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo.
Atanelishvili, Ilia
M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo. [electronic resource] - Translational research : the journal of laboratory and clinical medicine Apr 2016 - 99-111 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1878-1810
10.1016/j.trsl.2015.12.009 doi
Amino Acid Sequence
Animals
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Caspase 3--metabolism
Cell Survival--drug effects
Cells, Cultured
Collagen--metabolism
Disease Models, Animal
Fibroblasts--drug effects
Humans
Lung--cytology
Male
Mice, Inbred C57BL
Molecular Sequence Data
Peptide Fragments--metabolism
Proto-Oncogene Proteins c-met--metabolism
Pulmonary Fibrosis--drug therapy
Scleroderma, Systemic--drug therapy
Skin--cytology
Smad2 Protein--metabolism
M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo. [electronic resource] - Translational research : the journal of laboratory and clinical medicine Apr 2016 - 99-111 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1878-1810
10.1016/j.trsl.2015.12.009 doi
Amino Acid Sequence
Animals
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Caspase 3--metabolism
Cell Survival--drug effects
Cells, Cultured
Collagen--metabolism
Disease Models, Animal
Fibroblasts--drug effects
Humans
Lung--cytology
Male
Mice, Inbred C57BL
Molecular Sequence Data
Peptide Fragments--metabolism
Proto-Oncogene Proteins c-met--metabolism
Pulmonary Fibrosis--drug therapy
Scleroderma, Systemic--drug therapy
Skin--cytology
Smad2 Protein--metabolism