A variant in 3'-untranslated region of KRAS compromises its interaction with hsa-let-7g and contributes to the development of lung cancer in patients with COPD.
Hu, Hua
A variant in 3'-untranslated region of KRAS compromises its interaction with hsa-let-7g and contributes to the development of lung cancer in patients with COPD. [electronic resource] - International journal of chronic obstructive pulmonary disease 2015 - 1641-9 p. digital
Publication Type: Journal Article
1178-2005
10.2147/COPD.S83596 doi
3' Untranslated Regions
Aged
Base Sequence
Binding Sites
Cell Line, Tumor
Chi-Square Distribution
Female
Gene Expression Regulation, Neoplastic
Gene Frequency
Genes, Reporter
Genetic Predisposition to Disease
Humans
Luciferases--biosynthesis
Lung Neoplasms--genetics
Male
MicroRNAs--genetics
Middle Aged
Molecular Sequence Data
Odds Ratio
Polymorphism, Single Nucleotide
Proto-Oncogene Proteins p21(ras)--genetics
Pulmonary Disease, Chronic Obstructive--complications
RNA, Messenger--genetics
Risk Assessment
Risk Factors
Smoking--adverse effects
Transfection
A variant in 3'-untranslated region of KRAS compromises its interaction with hsa-let-7g and contributes to the development of lung cancer in patients with COPD. [electronic resource] - International journal of chronic obstructive pulmonary disease 2015 - 1641-9 p. digital
Publication Type: Journal Article
1178-2005
10.2147/COPD.S83596 doi
3' Untranslated Regions
Aged
Base Sequence
Binding Sites
Cell Line, Tumor
Chi-Square Distribution
Female
Gene Expression Regulation, Neoplastic
Gene Frequency
Genes, Reporter
Genetic Predisposition to Disease
Humans
Luciferases--biosynthesis
Lung Neoplasms--genetics
Male
MicroRNAs--genetics
Middle Aged
Molecular Sequence Data
Odds Ratio
Polymorphism, Single Nucleotide
Proto-Oncogene Proteins p21(ras)--genetics
Pulmonary Disease, Chronic Obstructive--complications
RNA, Messenger--genetics
Risk Assessment
Risk Factors
Smoking--adverse effects
Transfection