Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes.

Yip, Linda

Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes. [electronic resource] - Diabetes Feb 2015 - 604-17 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1939-327X

10.2337/db14-0803 doi


Aging
Alternative Splicing
Animals
Blood Glucose
Cell Cycle Proteins--genetics
DNA-Binding Proteins
Diabetes Mellitus, Type 1--genetics
Female
HEK293 Cells
Humans
Hyperglycemia--metabolism
Inflammation--metabolism
Islets of Langerhans--cytology
Lymph Nodes--physiology
Mice
Mice, Inbred NOD
Mice, SCID
Nerve Tissue Proteins--genetics
Nuclear Proteins--genetics
Pancreas--physiology
Pancreatic Elastase--genetics
Polypyrimidine Tract-Binding Protein--genetics
RNA-Binding Proteins--genetics
Repressor Proteins--genetics
Serine-Arginine Splicing Factors
Spleen--cytology
Transcription Factors--genetics