Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation.

Carlson, Thaddeus J

Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Mar 2014 - 2167-76 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1550-6606

10.4049/jimmunol.1302316 doi


Amino Acids--deficiency
Animals
Encephalomyelitis, Autoimmune, Experimental--genetics
Inflammation--chemically induced
Interleukin-23--genetics
Lymphocyte Activation
Mice
Mice, Inbred BALB C
Mice, Knockout
Phosphorylation--genetics
Piperidines
Quinazolinones
Receptors, CCR6--genetics
Receptors, Interleukin--genetics
STAT3 Transcription Factor--genetics
Th17 Cells--immunology