Tumor necrosis factor-α accelerates the resolution of established pulmonary fibrosis in mice by targeting profibrotic lung macrophages.

Redente, Elizabeth F

Tumor necrosis factor-α accelerates the resolution of established pulmonary fibrosis in mice by targeting profibrotic lung macrophages. [electronic resource] - American journal of respiratory cell and molecular biology Apr 2014 - 825-37 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1535-4989

10.1165/rcmb.2013-0386OC doi


Animals
Bleomycin
Cells, Cultured
Disease Models, Animal
Hydroxyproline--metabolism
Idiopathic Pulmonary Fibrosis--drug therapy
Lung--drug effects
Lung Compliance
Macrophages, Alveolar--drug effects
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Receptor, Macrophage Colony-Stimulating Factor--genetics
Recovery of Function
Remission Induction
Tacrolimus Binding Proteins--genetics
Time Factors
Tumor Necrosis Factor-alpha--deficiency
fas Receptor--genetics