Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression.

Gopinath, Sreelatha

Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression. [electronic resource] - Carcinogenesis Mar 2013 - 550-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1460-2180

10.1093/carcin/bgs375 doi


AC133 Antigen
Animals
Antigens, CD--metabolism
Cathepsin B--genetics
Cell Line, Tumor
Cell Proliferation
Cell Separation
Female
Flow Cytometry
Gene Expression
Gene Expression Regulation, Neoplastic
Gene Knockdown Techniques
Glioma--metabolism
Glycoproteins--metabolism
Hedgehog Proteins--metabolism
Humans
Mice
Mice, Nude
Neoplasm Transplantation
Neoplastic Stem Cells--metabolism
Peptides--metabolism
Polycomb Repressive Complex 1--genetics
RNA, Small Interfering--genetics
Receptors, Urokinase Plasminogen Activator--genetics
SOXB1 Transcription Factors--genetics
Signal Transduction
Transcription Factors--metabolism
Transcriptional Activation
Zinc Finger Protein GLI1