Complement C3a-induced IL-17 plays a critical role in an IgE-mediated late-phase asthmatic response and airway hyperresponsiveness via neutrophilic inflammation in mice.

Mizutani, Nobuaki

Complement C3a-induced IL-17 plays a critical role in an IgE-mediated late-phase asthmatic response and airway hyperresponsiveness via neutrophilic inflammation in mice. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Jun 2012 - 5694-705 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1550-6606

10.4049/jimmunol.1103176 doi


Animals
Antibodies, Monoclonal--physiology
Asthma--immunology
Bronchial Hyperreactivity--immunology
CD4-Positive T-Lymphocytes--immunology
Complement C3a--antagonists & inhibitors
Immunoglobulin E--physiology
Inflammation Mediators--antagonists & inhibitors
Interleukin-17--biosynthesis
Male
Mice
Mice, Inbred BALB C
Neutrophils--immunology
Receptors, Complement--antagonists & inhibitors
Time Factors