Turmeric (Curcuma longa) inhibits inflammatory nuclear factor (NF)-κB and NF-κB-regulated gene products and induces death receptors leading to suppressed proliferation, induced chemosensitization, and suppressed osteoclastogenesis.
Kim, Ji H
Turmeric (Curcuma longa) inhibits inflammatory nuclear factor (NF)-κB and NF-κB-regulated gene products and induces death receptors leading to suppressed proliferation, induced chemosensitization, and suppressed osteoclastogenesis. [electronic resource] - Molecular nutrition & food research Mar 2012 - 454-65 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1613-4133
10.1002/mnfr.201100270 doi
Animals
Anti-Inflammatory Agents--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Blotting, Western
Capecitabine
Cell Differentiation--drug effects
Cell Proliferation--drug effects
Curcuma--chemistry
Cyclin D1--genetics
Deoxycytidine--analogs & derivatives
Down-Regulation
Fluorouracil--analogs & derivatives
HCT116 Cells
HT29 Cells
Humans
Mice
NF-kappa B--antagonists & inhibitors
Osteoclasts--cytology
Paclitaxel--pharmacology
Plant Extracts--pharmacology
RANK Ligand--genetics
Reactive Oxygen Species--metabolism
Receptors, CXCR4--genetics
Receptors, Death Domain--genetics
STAT3 Transcription Factor--genetics
X-Linked Inhibitor of Apoptosis Protein--genetics
bcl-2-Associated X Protein--genetics
Turmeric (Curcuma longa) inhibits inflammatory nuclear factor (NF)-κB and NF-κB-regulated gene products and induces death receptors leading to suppressed proliferation, induced chemosensitization, and suppressed osteoclastogenesis. [electronic resource] - Molecular nutrition & food research Mar 2012 - 454-65 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1613-4133
10.1002/mnfr.201100270 doi
Animals
Anti-Inflammatory Agents--pharmacology
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Blotting, Western
Capecitabine
Cell Differentiation--drug effects
Cell Proliferation--drug effects
Curcuma--chemistry
Cyclin D1--genetics
Deoxycytidine--analogs & derivatives
Down-Regulation
Fluorouracil--analogs & derivatives
HCT116 Cells
HT29 Cells
Humans
Mice
NF-kappa B--antagonists & inhibitors
Osteoclasts--cytology
Paclitaxel--pharmacology
Plant Extracts--pharmacology
RANK Ligand--genetics
Reactive Oxygen Species--metabolism
Receptors, CXCR4--genetics
Receptors, Death Domain--genetics
STAT3 Transcription Factor--genetics
X-Linked Inhibitor of Apoptosis Protein--genetics
bcl-2-Associated X Protein--genetics