Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway.
Farooq, Faraz
Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway. [electronic resource] - The Journal of clinical investigation Aug 2011 - 3042-50 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1558-8238
10.1172/JCI46276 doi
Animals
Disease Models, Animal
Endothelial Cells--cytology
Gene Expression Regulation
Humans
Mice
Motor Neurons--physiology
Muscular Atrophy, Spinal--metabolism
Neurons--metabolism
Prolactin--biosynthesis
RNA, Messenger--metabolism
STAT5 Transcription Factor--metabolism
Survival of Motor Neuron 1 Protein--biosynthesis
Transcription, Genetic
Tumor Suppressor Proteins--metabolism
Up-Regulation
Prolactin increases SMN expression and survival in a mouse model of severe spinal muscular atrophy via the STAT5 pathway. [electronic resource] - The Journal of clinical investigation Aug 2011 - 3042-50 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1558-8238
10.1172/JCI46276 doi
Animals
Disease Models, Animal
Endothelial Cells--cytology
Gene Expression Regulation
Humans
Mice
Motor Neurons--physiology
Muscular Atrophy, Spinal--metabolism
Neurons--metabolism
Prolactin--biosynthesis
RNA, Messenger--metabolism
STAT5 Transcription Factor--metabolism
Survival of Motor Neuron 1 Protein--biosynthesis
Transcription, Genetic
Tumor Suppressor Proteins--metabolism
Up-Regulation