Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ).
Bachstetter, Adam D
Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ). [electronic resource] - Journal of neuroinflammation Jul 2011 - 79 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1742-2094
10.1186/1742-2094-8-79 doi
Amyloid beta-Peptides--pharmacology
Animals
Cell Line
Cytokines--metabolism
Female
Interleukin-1beta--metabolism
Ligands
Lipopolysaccharides--pharmacology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Microglia--cytology
Mitogen-Activated Protein Kinase 14--antagonists & inhibitors
Peptide Fragments--pharmacology
Pyridazines--metabolism
Pyrimidines--metabolism
Rats
Rats, Sprague-Dawley
Signal Transduction--physiology
Toll-Like Receptors--agonists
Tumor Necrosis Factor-alpha--metabolism
Up-Regulation--drug effects
Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ). [electronic resource] - Journal of neuroinflammation Jul 2011 - 79 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1742-2094
10.1186/1742-2094-8-79 doi
Amyloid beta-Peptides--pharmacology
Animals
Cell Line
Cytokines--metabolism
Female
Interleukin-1beta--metabolism
Ligands
Lipopolysaccharides--pharmacology
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Microglia--cytology
Mitogen-Activated Protein Kinase 14--antagonists & inhibitors
Peptide Fragments--pharmacology
Pyridazines--metabolism
Pyrimidines--metabolism
Rats
Rats, Sprague-Dawley
Signal Transduction--physiology
Toll-Like Receptors--agonists
Tumor Necrosis Factor-alpha--metabolism
Up-Regulation--drug effects