Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis.
Farina, Giuseppina A
Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis. [electronic resource] - The Journal of investigative dermatology Nov 2010 - 2583-93 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1523-1747
10.1038/jid.2010.200 doi
Adaptor Proteins, Vesicular Transport--genetics
Animals
Cells, Cultured
Dermatitis--genetics
Dermis--immunology
Disease Models, Animal
Fibroblasts--cytology
GTP-Binding Proteins--metabolism
Gene Expression--immunology
Humans
Interferon Type I--immunology
Interferon-gamma--immunology
Lupus Erythematosus, Cutaneous--genetics
Mice
Mice, Inbred C57BL
Mice, Mutant Strains
Myxovirus Resistance Proteins
Poly I-C--metabolism
Scleroderma, Systemic--genetics
Toll-Like Receptor 3--agonists
Transforming Growth Factor beta--immunology
Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis. [electronic resource] - The Journal of investigative dermatology Nov 2010 - 2583-93 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1523-1747
10.1038/jid.2010.200 doi
Adaptor Proteins, Vesicular Transport--genetics
Animals
Cells, Cultured
Dermatitis--genetics
Dermis--immunology
Disease Models, Animal
Fibroblasts--cytology
GTP-Binding Proteins--metabolism
Gene Expression--immunology
Humans
Interferon Type I--immunology
Interferon-gamma--immunology
Lupus Erythematosus, Cutaneous--genetics
Mice
Mice, Inbred C57BL
Mice, Mutant Strains
Myxovirus Resistance Proteins
Poly I-C--metabolism
Scleroderma, Systemic--genetics
Toll-Like Receptor 3--agonists
Transforming Growth Factor beta--immunology