Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Abeta1-40.
Sondag, Cindy M
Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Abeta1-40. [electronic resource] - Journal of neuroinflammation Mar 2010 - 22 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1742-2094
10.1186/1742-2094-7-22 doi
Amyloid beta-Peptides--metabolism
Amyloid beta-Protein Precursor--physiology
Blotting, Western
Brain Chemistry--physiology
Cell Adhesion--physiology
Cell Line
Cerebrovascular Circulation--physiology
Collagen Type I--metabolism
Enzyme-Linked Immunosorbent Assay
Humans
Immunoprecipitation
Inflammation--pathology
Interleukin-1beta--metabolism
Peptide Fragments--metabolism
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--physiology
RNA, Small Interfering
Signal Transduction--physiology
Transfection
p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors
src-Family Kinases--antagonists & inhibitors
Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Abeta1-40. [electronic resource] - Journal of neuroinflammation Mar 2010 - 22 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1742-2094
10.1186/1742-2094-7-22 doi
Amyloid beta-Peptides--metabolism
Amyloid beta-Protein Precursor--physiology
Blotting, Western
Brain Chemistry--physiology
Cell Adhesion--physiology
Cell Line
Cerebrovascular Circulation--physiology
Collagen Type I--metabolism
Enzyme-Linked Immunosorbent Assay
Humans
Immunoprecipitation
Inflammation--pathology
Interleukin-1beta--metabolism
Peptide Fragments--metabolism
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--physiology
RNA, Small Interfering
Signal Transduction--physiology
Transfection
p38 Mitogen-Activated Protein Kinases--antagonists & inhibitors
src-Family Kinases--antagonists & inhibitors