Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers.
Liu, Y
Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers. [electronic resource] - Oncogene Dec 2008 - 6729-37 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
1476-5594
10.1038/onc.2008.322 doi
Apoptosis
Cell Line, Tumor
Colorectal Neoplasms--enzymology
Cyclooxygenase 2--genetics
Dinoprostone--metabolism
Down-Regulation
ErbB Receptors--genetics
Gene Expression Regulation, Neoplastic
Glycogen Synthase Kinase 3--genetics
Glycogen Synthase Kinase 3 beta
Humans
Mitochondrial Proteins--biosynthesis
Phosphorylation
Proline--genetics
Proline Oxidase--biosynthesis
Reactive Oxygen Species--metabolism
Signal Transduction
Transcription, Genetic
Tumor Suppressor Protein p53--genetics
Wnt Proteins--genetics
beta Catenin--genetics
Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers. [electronic resource] - Oncogene Dec 2008 - 6729-37 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
1476-5594
10.1038/onc.2008.322 doi
Apoptosis
Cell Line, Tumor
Colorectal Neoplasms--enzymology
Cyclooxygenase 2--genetics
Dinoprostone--metabolism
Down-Regulation
ErbB Receptors--genetics
Gene Expression Regulation, Neoplastic
Glycogen Synthase Kinase 3--genetics
Glycogen Synthase Kinase 3 beta
Humans
Mitochondrial Proteins--biosynthesis
Phosphorylation
Proline--genetics
Proline Oxidase--biosynthesis
Reactive Oxygen Species--metabolism
Signal Transduction
Transcription, Genetic
Tumor Suppressor Protein p53--genetics
Wnt Proteins--genetics
beta Catenin--genetics